Description

tert-Butyl 4-((6-Aminopyridin-3-Yl)Methyl)Piperazine-1-Carboxylate CAS NO 1178566-52-3 is a high-purity, advanced pharmaceutical intermediate featuring a piperazine core linked to an aminopyridine moiety. This compound is crucial for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries to create potential drug candidates targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) and improve pharmacokinetic properties.
• API Development: Serves as a critical precursor in the scalable process development and manufacturing of potential new chemical entities (NCEs).
• Bioconjugation & Probe Synthesis: The reactive amine group allows for conjugation, useful in creating chemical probes for biological target identification and validation.
• Library Synthesis: Employed in combinatorial and parallel synthesis to generate diverse compound libraries for high-throughput screening (HTS).

Basic Information

Product Name	tert-Butyl 4-((6-Aminopyridin-3-Yl)Methyl)Piperazine-1-Carboxylate
CAS No.	1178566-52-3
Molecular Formula	C15H24N4O2
Molecular Weight	292.38 g/mol
Synonyms	1-Boc-4-((6-Amino-3-pyridyl)methyl)piperazine; tert-Butyl 4-[(6-Amino-3-pyridinyl)methyl]-1-piperazinecarboxylate; 4-((6-Aminopyridin-3-yl)methyl)piperazine-1-carboxylic acid tert-butyl ester; 1-Piperazinecarboxylic acid, 4-[(6-amino-3-pyridinyl)methyl]-, 1,1-dimethylethyl ester; Boc-4-(6-aminopyridin-3-ylmethyl)piperazine; 1178566-52-3; tert-Butyl 4-(6-aminopyridin-3-ylmethyl)piperazine-1-carboxylate
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-((6-Aminopyridin-3-Yl)Methyl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.