Description

Ethyl 2-Amino-3-(Trifluoromethyl)Benzoate is a high-value trifluoromethylated benzoate ester derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both an amino group and a trifluoromethyl substituent, makes it a versatile building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the trifluoromethyl group can enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or intermediate for developing specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: A valuable reagent for medicinal chemistry, process chemistry, and methodology development in academic and industrial laboratories.
• Fluorine Chemistry: Essential for introducing the trifluoromethyl moiety into complex molecular architectures, a common strategy in modern drug design.

Basic Information

Product Name	Ethyl 2-Amino-3-(Trifluoromethyl)Benzoate
CAS No.	1178318-66-5
Molecular Formula	C10H10F3NO2
Molecular Weight	233.19 g/mol
Synonyms	2-Amino-3-(trifluoromethyl)benzoic acid ethyl ester; Ethyl 2-amino-α,α,α-trifluoro-m-toluate; Benzoic acid, 2-amino-3-(trifluoromethyl)-, ethyl ester; Ethyl 2-amino-3-trifluoromethylbenzoate; 3-(Trifluoromethyl)anthranilic acid ethyl ester; m-Trifluoromethylanthranilic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-Amino-3-(Trifluoromethyl)Benzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.