Description

5-(Propan-2-Yl)-1-(Pyridin-2-Yl)-1H-Pyrazole-3-Carboxylic Acid CAS NO 1177330-29-8 is a high-purity pyrazole-carboxylic acid derivative, a key advanced pharmaceutical intermediate (API) and versatile building block in organic synthesis. Its molecular structure, featuring both pyrazole and pyridine rings, makes it a critical precursor for developing novel active compounds. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create new molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: Serves as a core building block for the synthesis of novel drug candidates, particularly in therapeutic areas requiring complex heterocyclic scaffolds.
• Agrochemical Research: Used in the development of new pesticides, herbicides, and fungicides where the pyrazole moiety is a key active component.
• Ligand Synthesis: Acts as a precursor for creating specialized ligands used in catalysis and material science applications.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting exploratory synthetic chemistry.
• Fine Chemical Production: Integrated into multi-step synthesis processes for producing high-value, complex organic molecules.

Basic Information

Item	Detail
Product Name	5-(Propan-2-Yl)-1-(Pyridin-2-Yl)-1H-Pyrazole-3-Carboxylic Acid
CAS No.	1177330-29-8
Molecular Formula	C12H13N3O2
Molecular Weight	231.25 g/mol
Synonyms	1-(Pyridin-2-yl)-5-(propan-2-yl)-1H-pyrazole-3-carboxylic acid; 5-Isopropyl-1-(2-pyridyl)-1H-pyrazole-3-carboxylic acid; 2-Pyridine, 1H-Pyrazole-3-carboxylic acid derivative; 1177330-29-8; 5-(1-Methylethyl)-1-(2-pyridinyl)-1H-pyrazole-3-carboxylic acid; Isopropyl-pyridyl-pyrazolecarboxylic acid
EINECS	Contact for details

Quality Control

Our 5-(Propan-2-Yl)-1-(Pyridin-2-Yl)-1H-Pyrazole-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.