Description

7-Chloro-4-Methyl-n-(Pyridin-4-Ylmethyl)-1,3-Benzothiazol-2-Amine is a high-purity, advanced pharmaceutical intermediate with a distinct benzothiazole-pyridine hybrid structure. This compound matters for its critical role as a key building block in the synthesis of novel bioactive molecules, particularly in medicinal chemistry research and development. Pharmaceutical companies and contract research organizations (CROs) need it to develop new drug candidates targeting a range of therapeutic areas, where its specific scaffold offers valuable structure-activity relationship (SAR) exploration.

Application

• Pharmaceutical Intermediate: Serves as a core scaffold for the research and synthesis of new chemical entities (NCEs) in drug discovery programs.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• Kinase Inhibitor Development: A potential precursor in the synthesis of small molecule inhibitors targeting various kinase enzymes involved in disease pathways.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying biological processes and target validation.
• Agrochemical Research: May be investigated as an intermediate for developing novel active ingredients with herbicidal or pesticidal properties.
• Material Science: Its fused heterocyclic system can be explored for creating novel organic electronic materials or ligands for catalysis.

Basic Information

Product Name	7-Chloro-4-Methyl-n-(Pyridin-4-Ylmethyl)-1,3-Benzothiazol-2-Amine
CAS No.	1177306-69-2
Molecular Formula	C14H12ClN3S
Molecular Weight	289.78 g/mol
Synonyms	7-Chloro-4-methyl-N-[(pyridin-4-yl)methyl]-1,3-benzothiazol-2-amine; 2-Amino-7-chloro-4-methyl-N-(4-pyridinylmethyl)benzothiazole; 7-Chloro-4-methyl-N-(4-pyridinylmethyl)-2-benzothiazolamine; 1177306-69-2; 7-Chloro-4-methyl-N-(pyridin-4-ylmethyl)benzo[d]thiazol-2-amine; N-((Pyridin-4-yl)methyl)-7-chloro-4-methylbenzo[d]thiazol-2-amine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for advanced pharmaceutical intermediates. Every batch is characterized and controlled using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to confirm identity, purity, and consistency. Certificates of Analysis (COA) are available upon request, providing full transparency on all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.