Description

1-[1-(4-Fluorophenyl)-1H-Pyrazol-4-Yl]Ethanone is a high-purity fluorinated pyrazole derivative, serving as a critical advanced intermediate in modern organic synthesis. This compound is valued for its precise molecular architecture, which enables the construction of complex pharmacophores and functional materials. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorinated pyrazole core.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for OLEDs or molecular sensors.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and cellular pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up production under cGMP conditions for clinical trial materials.

Basic Information

Product Name	1-[1-(4-Fluorophenyl)-1H-Pyrazol-4-Yl]Ethanone
CAS No.	1177283-25-8
Molecular Formula	C11H9FN2O
Molecular Weight	204.20 g/mol
Synonyms	4-Acetyl-1-(4-fluorophenyl)-1H-pyrazole; 1-(1-(4-Fluorophenyl)-1H-pyrazol-4-yl)ethanone; 1-(4-Fluorophenyl)-1H-pyrazole-4-yl methyl ketone; 4-Acetyl-1-(4-fluorophenyl)pyrazole; 1-(4-Fluorophenyl)-4-acetylpyrazole; 4-Acetyl-1-(p-fluorophenyl)pyrazole; 1-(p-Fluorophenyl)-1H-pyrazol-4-yl ethanone
EINECS	Contact for details

Quality Control

Our production of 1-[1-(4-Fluorophenyl)-1H-Pyrazol-4-Yl]Ethanone adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data including HPLC purity, NMR confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is supplied with each batch, and custom synthesis can be performed to meet specific pharmacopeial or internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.