Description

n-2-Hydroxybenzyl-L-Serine Methyl Ester is a specialized chiral amino acid derivative, serving as a crucial building block in advanced organic synthesis. Its value lies in its bifunctional structure, incorporating both a phenolic hydroxyl group and a serine ester moiety, which enables its use in constructing complex molecular architectures. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel peptides, enzyme inhibitors, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in peptide-based drug discovery.
• Peptide Synthesis: Used as a modified serine residue in solid-phase and solution-phase peptide synthesis to introduce specific functional handles or alter peptide properties.
• Ligand and Chelator Development: The salicylaldehyde-like structure makes it a precursor for creating Schiff base ligands used in catalysis and metal chelation studies.
• Bioconjugation Chemistry: Serves as a linker or spacer molecule for attaching drugs, probes, or other functionalities to biomolecules like proteins or antibodies.
• Chemical Biology Research: Employed as a tool compound to study enzyme mechanisms or to develop enzyme inhibitors targeting specific biological pathways.
• Material Science: Potential monomer or cross-linking agent in the synthesis of specialized polymers with unique chemical or biological properties.

Basic Information

Product Name	n-2-Hydroxybenzyl-L-Serine Methyl Ester
CAS No.	1176623-78-1
Molecular Formula	C11H15NO4
Molecular Weight	225.24 g/mol
Synonyms	L-Serine, N-(2-hydroxybenzyl)-, methyl ester; Methyl N-(2-hydroxybenzyl)-L-serinate; N-Salicyl-L-serine methyl ester; (2S)-2-Amino-3-[(2-hydroxyphenyl)methoxy]propanoic acid methyl ester; 2-Hydroxybenzyl-L-serine methyl ester; O-(2-Hydroxybenzyl)-L-serine methyl ester
EINECS	Contact for details

Quality Control

Our n-2-Hydroxybenzyl-L-Serine Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.