Description

5-Methyl-2,3-Dihydro-1,8-Naphthyridin-4(1H)-One is a high-purity, advanced pharmaceutical intermediate and heterocyclic building block of significant importance in modern organic synthesis. This compound serves as a critical scaffold for medicinal chemistry research and development, enabling the creation of novel bioactive molecules. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Core scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities in drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that utilize naphthyridine-based chemistry.
• Fine Chemical Production: Serves as a precursor for the manufacture of specialty chemicals, dyes, and functional materials requiring complex heterocyclic structures.
• Ligand and Catalyst Development: Potential use in creating novel chelating ligands or organocatalysts for asymmetric synthesis and metal complexation.

Basic Information

Product Name	5-Methyl-2,3-Dihydro-1,8-Naphthyridin-4(1H)-One
CAS No.	1176517-83-1
Molecular Formula	C9H10N2O
Molecular Weight	162.19 g/mol
Synonyms	5-Methyl-1,2,3,4-tetrahydro-1,8-naphthyridin-4-one; 5-Methyl-1,2,3,4-tetrahydro-8-naphthyridin-4-one; 5-Methyl-2,3-dihydro-1H-1,8-naphthyridin-4-one; 4(1H)-One, 5-methyl-2,3-dihydro-1,8-naphthyridin-; 5-Methyl-4-oxo-1,2,3,4-tetrahydro-1,8-naphthyridine
EINECS	Contact for details

Quality Control

Our 5-Methyl-2,3-Dihydro-1,8-Naphthyridin-4(1H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.