Description

Fmoc-D-Orn(N3)-Oh is a specialized, non-proteinogenic amino acid derivative designed for advanced peptide synthesis. This compound is critical for researchers and manufacturers requiring precise structural control and the introduction of bioorthogonal functional groups, such as azides, into peptide chains. It is primarily utilized in pharmaceutical R&D, proteomics, and the development of novel bioconjugates and drug delivery systems. The product is supplied under stringent quality controls to ensure batch-to-batch consistency for sensitive applications.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key building block for the Fmoc-strategy, enabling the incorporation of D-ornithine with an azide side chain.
• Click Chemistry Conjugation: The azide (N3) functional group allows for efficient, site-specific bioconjugation via copper-catalyzed azide-alkyne cycloaddition (CuAAC).
• Drug Discovery & Development: Used to create peptide-based drug candidates, probes, and tools with tailored physicochemical properties and labeling sites.
• Bioconjugate and ADC Development: Facilitates the stable attachment of payloads (e.g., toxins, dyes, polymers) to peptides or proteins for targeted therapies and diagnostics.
• Chemical Biology Research: Serves as a versatile tool for studying protein-protein interactions, enzyme activity, and cellular processes through labeled peptides.
• Material Science: Used to functionalize surfaces and materials with bioactive peptide sequences for biomedical engineering applications.

Basic Information

Product Name	Fmoc-D-Orn(N3)-Oh
CAS No.	1176270-25-9
Molecular Formula	C₂₀H₂₁N₅O₄
Molecular Weight	395.41 g/mol
Synonyms	Fmoc-D-ornithine(N3)-OH; N-α-Fmoc-N-δ-azido-D-ornithine; Fmoc-D-Orn(N₃)-OH; (2R)-5-Azido-2-[(9H-fluoren-9-ylmethoxy)carbonylamino]pentanoic acid; N-δ-Azido-N-α-[(9-fluorenylmethyloxy)carbonyl]-D-ornithine; Fmoc-D-Lys(N3)-OH analog; Fmoc-D-Azidoornithine; D-ornithine derivative, Fmoc-protected, N3-functionalized
EINECS	Contact for details

Quality Control

Our Fmoc-D-Orn(N3)-Oh is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure it meets the high-purity standards required for peptide synthesis and bioconjugation. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to strict quality management protocols to guarantee supply reliability and product consistency for our global B2B clients in research and pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This compound is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	95.0% - 102.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.