Description

6-(4-Methylpiperazin-1-yl)pyridine-2-carbonitrile is a high-purity, heterocyclic organic compound featuring a pyridine core substituted with a nitrile group and a 4-methylpiperazine moiety. This versatile chemical building block is crucial for the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing novel active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the creation of novel pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for designing specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of organic semiconductors, conductive polymers, or advanced organic frameworks.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	6-(4-Methylpiperazin-1-yl)pyridine-2-carbonitrile
CAS No.	1175689-23-2
Molecular Formula	C11H14N4
Molecular Weight	202.26 g/mol
Synonyms	2-Cyano-6-(4-methyl-1-piperazinyl)pyridine; 6-(4-Methyl-1-piperazinyl)-2-pyridinecarbonitrile; 6-(4-Methylpiperazin-1-yl)picolinonitrile; 2-Pyridinecarbonitrile, 6-(4-methyl-1-piperazinyl)-; 6-(N-Methylpiperazinyl)-2-cyanopyridine; 6-(4-Methylpiperazino)-2-cyanopyridine; 6-(4-Methylpiperazin-1-yl)-2-cyanopyridine
EINECS	Contact for details

Quality Control

Our 6-(4-Methylpiperazin-1-yl)pyridine-2-carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development and cGMP-grade requirements for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.