Description

Ethyl 3-Cyclopropyl-2-Methyl-6-Oxo-6,7-Dihydro-2H-Pyrazolo[3,4-B]Pyridine-4-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant commercial importance as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Organic Synthesis Building Block: Used in research-scale and pilot-scale organic reactions to construct complex fused pyrazolo-pyridine ring systems.
• Medicinal Chemistry Research: A valuable scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Process Chemistry Development: Employed in the development and optimization of scalable synthetic routes for potential API manufacturing.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and development services for the pharmaceutical industry.

Basic Information

Item	Detail
Product Name	Ethyl 3-Cyclopropyl-2-Methyl-6-Oxo-6,7-Dihydro-2H-Pyrazolo[3,4-B]Pyridine-4-Carboxylate
CAS No.	1174845-21-6
Molecular Formula	C15H17N3O3
Molecular Weight	287.32 g/mol
Synonyms	Ethyl 3-cyclopropyl-2-methyl-6-oxo-6,7-dihydro-2H-pyrazolo[3,4-b]pyridine-4-carboxylate; 4-Carbethoxy-3-cyclopropyl-2-methyl-2H-pyrazolo[3,4-b]pyridin-6(7H)-one; 2H-Pyrazolo[3,4-b]pyridine-4-carboxylic acid, 3-cyclopropyl-6,7-dihydro-2-methyl-6-oxo-, ethyl ester; 1174845-21-6; Ethyl 3-cyclopropyl-2-methyl-6-oxo-2,6-dihydro-7H-pyrazolo[3,4-b]pyridine-4-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 3-Cyclopropyl-2-Methyl-6-Oxo-6,7-Dihydro-2H-Pyrazolo[3,4-B]Pyridine-4-Carboxylate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical R&D and process chemistry. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.