Description

Ethyl 6-Hydroxy-5-Iodo-2-Methylnicotinate is a high-value, multi-functional heterocyclic building block featuring a halogenated pyridine core. This compound is essential for advanced organic synthesis, offering a versatile scaffold for constructing complex molecules with potential biological activity. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for use in medicinal chemistry, process development, and the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, or metabolic conditions.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, or insecticides, leveraging its halogenated nicotinate structure.
• Ligand & Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis or as a core structure for organocatalysts.
• Material Science: Potential building block for organic electronic materials, such as charge-transport layers or light-emitting components, due to its conjugated system.
• Chemical Biology Probe Synthesis: Utilized to create tagged molecules or activity-based probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects at various scales, from gram to kilogram.

Basic Information

Product Name	Ethyl 6-Hydroxy-5-Iodo-2-Methylnicotinate
CAS No.	1174665-76-9
Molecular Formula	C9H10INO3
Molecular Weight	307.09 g/mol
Synonyms	5-Iodo-6-hydroxy-2-methylnicotinic acid ethyl ester; Ethyl 5-iodo-6-hydroxy-2-picolinate; 2-Methyl-5-iodo-6-hydroxynicotinic acid ethyl ester; 6-Hydroxy-5-iodo-2-methylnicotinic acid ethyl ester; Ethyl 6-hydroxy-5-iodo-2-methylpyridine-3-carboxylate; 3-Carbethoxy-5-iodo-6-hydroxy-2-methylpyridine
EINECS	Contact for details

Quality Control

Every batch of Ethyl 6-Hydroxy-5-Iodo-2-Methylnicotinate is produced and tested under strict quality management protocols to ensure consistency and purity for critical R&D and scale-up applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as identity, purity, and impurity profiles. Our quality systems are designed to support development work under cGMP (current Good Manufacturing Practice) guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.