Description

Methyl 5-(Difluoromethoxy)Picolinate is a high-value, fluorinated pyridine derivative serving as a critical synthetic intermediate. This compound matters for its role in constructing complex molecules, particularly in the development of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of drug candidates, especially those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the difluoromethoxy group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for developing novel fluorinated ligands, catalysts, and functional materials.
• Organic Synthesis: A versatile reagent for introducing the 5-(difluoromethoxy)picolinoyl moiety into more complex molecular architectures in medicinal and process chemistry.

Basic Information

Item	Detail
Product Name	Methyl 5-(Difluoromethoxy)Picolinate
CAS No.	1174323-35-3
Molecular Formula	C8H7F2NO3
Molecular Weight	203.14 g/mol
Synonyms	5-(Difluoromethoxy)picolinic acid methyl ester; Methyl 5-(difluoromethoxy)pyridine-2-carboxylate; 2-Pyridinecarboxylic acid, 5-(difluoromethoxy)-, methyl ester; Methyl 5-(difluoromethoxy)-2-pyridinecarboxylate; 5-(Difluoromethoxy)-2-pyridinecarboxylic acid methyl ester; Methyl 5-(difluoromethoxy)picolinate (CAS 1174323-35-3)
EINECS	Contact for details

Quality Control

Our Methyl 5-(Difluoromethoxy)Picolinate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.