Description

4-Isocyanato-1-Methyl-1H-Pyrazole is a specialized heterocyclic isocyanate building block with the CAS registry number 1174064-57-3. This compound is a critical intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs) due to its highly reactive isocyanate group. It is primarily utilized by R&D chemists and process engineers in the pharmaceutical, agrochemical, and polymer industries for developing novel compounds with tailored properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor research.
• Agrochemical Synthesis: Used in creating advanced pesticides and herbicides with specific biological activity.
• Polymer Modification: Serves as a cross-linking agent or functional monomer for producing polyurethanes and other specialty polymers with enhanced thermal or chemical resistance.
• Chemical Research (R&D): Essential reagent in medicinal chemistry and material science for constructing diverse heterocyclic libraries.
• Ligand and Catalyst Development: Used to prepare functionalized pyrazole-based ligands for metal complexes in catalytic applications.

Basic Information

Product Name	4-Isocyanato-1-Methyl-1H-Pyrazole
CAS No.	1174064-57-3
Molecular Formula	C5H5N3O
Molecular Weight	123.11 g/mol
Synonyms	1-Methyl-4-isocyanato-1H-pyrazole; 1-Methyl-1H-pyrazole-4-isocyanate; 4-Isocyanato-1-methylpyrazole; 1-Methylpyrazole-4-isocyanate; 1-Methyl-1H-4-pyrazole isocyanate; 4-Isocyanato-1-methyl-1H-pyrazole; Pyrazole-4-isocyanate, 1-methyl-
EINECS	Contact for details

Quality Control

Our 4-Isocyanato-1-Methyl-1H-Pyrazole is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP standards where applicable to meet the stringent requirements of our pharmaceutical and advanced material clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.