Description

4-Ethoxy-1-(4-Fluorophenyl)-2-Oxo-1,2-Dihydropyridine-3-Carboxylicacid is a high-purity, advanced pharmaceutical intermediate characterized by its specific dihydropyridine carboxylic acid structure. This compound is of critical importance for research and development in medicinal chemistry, serving as a key building block for synthesizing novel active pharmaceutical ingredients (APIs). It is primarily needed by pharmaceutical manufacturers, contract research organizations (CROs), and academic research institutions focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural component in the multi-step synthesis of potential APIs.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.
• Academic & Institutional Research: Utilized in university and institutional labs for exploratory research in heterocyclic and fluorine chemistry.
• Reference Standard: Can be supplied as a high-purity analytical standard for method development and quality control in API production.

Basic Information

Product Name	4-Ethoxy-1-(4-Fluorophenyl)-2-Oxo-1,2-Dihydropyridine-3-Carboxylicacid
CAS No.	1174046-90-2
Molecular Formula	C14H12FNO4
Molecular Weight	277.25 g/mol
Synonyms	4-Ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxylic acid; 1-(4-Fluorophenyl)-4-ethoxy-2-oxo-1,2-dihydropyridine-3-carboxylic acid; 1174046-90-2; 4-Ethoxy-1-(p-fluorophenyl)-2-oxo-1,2-dihydro-3-pyridinecarboxylic acid; 3-Pyridinecarboxylic acid, 1-(4-fluorophenyl)-4-ethoxy-1,2-dihydro-2-oxo-; 1,2-Dihydro-1-(4-fluorophenyl)-4-ethoxy-2-oxo-3-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 4-Ethoxy-1-(4-Fluorophenyl)-2-Oxo-1,2-Dihydropyridine-3-Carboxylicacid is manufactured under strict quality management systems. We provide material suitable for research and development use, with purity typically exceeding 97% (HPLC). Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. For cGMP-grade material intended for pharmaceutical development, please contact our technical sales team for specific quality agreements and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.