Description

5-Bromo-6-Methyl-Nicotinic Acid Methyl Ester is a high-value, multi-functional pyridine derivative and a key synthetic intermediate in advanced organic chemistry. This compound is essential for researchers and manufacturers requiring precise bromination and esterification sites on a nicotinic acid scaffold for constructing complex molecular architectures. It is primarily utilized by the pharmaceutical, agrochemical, and specialty chemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated pyridine structure.
• Ligand and Catalyst Development: Employed in organometallic chemistry for the creation of novel ligands and catalysts used in cross-coupling reactions.
• Material Science Research: Acts as a precursor for functionalized organic molecules used in electronic materials and organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	5-Bromo-6-Methyl-Nicotinic Acid Methyl Ester
CAS No.	1174028-22-8
Molecular Formula	C8H8BrNO2
Molecular Weight	230.06 g/mol
Synonyms	Methyl 5-bromo-6-methylnicotinate; 5-Bromo-6-methylpyridine-3-carboxylic acid methyl ester; 3-Pyridinecarboxylic acid, 5-bromo-6-methyl-, methyl ester; 5-Bromo-6-methyl-3-pyridinecarboxylic acid methyl ester; Methyl 5-bromo-6-methyl-3-pyridinecarboxylate; 5-Bromo-6-methylnicotinic acid methyl ester; Methyl 5-bromo-6-methylnicotinate (CAS 1174028-22-8)
EINECS	Contact for details

Quality Control

Our 5-Bromo-6-Methyl-Nicotinic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in GMP and ISO-regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.