Description

(S)-Methyl 2-(1-(7-Methyl-2-Morpholino-4-Oxo-4H-Pyrido[1,2-A]Pyrimidin-9-Yl)Ethylamino)Benzoate is a high-purity, advanced pharmaceutical intermediate with a defined stereochemistry. This compound is critical for the research and development of novel therapeutic agents, particularly in the field of kinase inhibition. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of targeted kinase inhibitor drugs.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Preclinical Studies: Serves as a critical material for producing compounds for biological testing and pharmacokinetic evaluation.
• Process Chemistry: Employed in route scouting and scale-up development for new chemical entities (NCEs).
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Reference Standard: Can be used as a high-purity analytical standard for method development and quality control.

Basic Information

Product Name	(S)-Methyl 2-(1-(7-Methyl-2-Morpholino-4-Oxo-4H-Pyrido[1,2-A]Pyrimidin-9-Yl)Ethylamino)Benzoate
CAS No.	1173900-38-3
Molecular Formula	C22H26N4O4
Molecular Weight	410.47 g/mol
Synonyms	(S)-Methyl 2-[[1-(7-Methyl-2-morpholin-4-yl-4-oxopyrido[1,2-a]pyrimidin-9-yl)ethyl]amino]benzoate; Methyl (S)-2-((1-(7-methyl-2-morpholino-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl)ethyl)amino)benzoate; 1173900-38-3; UNII-9QZ1H6B4S2; 9QZ1H6B4S2; Benzoic acid, 2-[[(1S)-1-(7-methyl-2-morpholin-4-yl-4-oxopyrido[1,2-a]pyrimidin-9-yl)ethyl]amino]-, methyl ester
EINECS	Contact for details

Quality Control

Our (S)-Methyl 2-(1-(7-Methyl-2-Morpholino-4-Oxo-4H-Pyrido[1,2-A]Pyrimidin-9-Yl)Ethylamino)Benzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity, to ensure compliance with stringent specifications for pharmaceutical intermediates. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under a dry atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.