Description

3-Aminocyclobutanecarboxylic Acid tert-Butyl Ester is a versatile, high-purity chemical building block essential for advanced organic synthesis. Its unique structure, featuring a cyclobutane ring with protected amine and carboxylic acid functionalities, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in protease inhibitor and constrained peptide analog research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides with novel modes of action.
• Peptidomimetics & Bioactive Molecules: The constrained cyclobutane scaffold is valuable for creating conformationally restricted peptides and other bioactive compounds.
• Ligand & Catalyst Development: Serves as a precursor for specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry and the exploration of new chemical space.
• Material Science Precursor: Potential use in the synthesis of specialty polymers and advanced materials with specific structural properties.

Basic Information

Product Name	3-Aminocyclobutanecarboxylic Acid tert-Butyl Ester
CAS No.	1173205-83-8
Molecular Formula	C9H17NO2
Molecular Weight	171.24 g/mol
Synonyms	3-Amino-1-Boc-cyclobutanecarboxylic acid; 1-(tert-Butoxycarbonyl)-3-aminocyclobutanecarboxylic acid; 3-((tert-Butoxycarbonyl)amino)cyclobutanecarboxylic acid; 3-Aminocyclobutanecarboxylic acid 1,1-dimethylethyl ester; 3-Boc-aminocyclobutanecarboxylic acid; tert-Butyl 3-aminocyclobutanecarboxylate; 3-Amino-cyclobutanecarboxylic acid tert-butyl ester; Boc-3-Acbc-OH
EINECS	Contact for details

Quality Control

Every batch of 3-Aminocyclobutanecarboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency. Our standard quality commitment includes comprehensive analysis via HPLC, NMR, and MS. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profile is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.