Description

tert-Butyl Bromoacetate-13C is a stable isotope-labeled analog of tert-butyl bromoacetate, where the carbonyl carbon is replaced with carbon-13. This compound is a critical building block in organic synthesis, particularly for the preparation of isotopically labeled compounds for research and development. It is primarily used by pharmaceutical, agrochemical, and academic research laboratories for applications in drug discovery, metabolic studies, and as an internal standard for analytical methods.

Application

• Synthesis of Carbon-13 Labeled Compounds: Essential for creating isotopically labeled intermediates in pharmaceutical and agrochemical research.
• Metabolic Pathway Tracing: Used in biochemical research to track metabolic pathways and study drug metabolism using mass spectrometry.
• Internal Standard for Analytical Chemistry: Serves as a high-purity internal standard in quantitative GC-MS and LC-MS analysis to ensure accuracy.
• Peptide and Protein Modification: Acts as a reagent for introducing labeled acetyl or other functional groups into biomolecules.
• Material Science Research: Employed in the synthesis of novel labeled polymers or materials for specialized research applications.
• NMR Spectroscopy Studies: Provides a distinct signal in NMR spectra for structural elucidation and mechanistic studies in synthetic chemistry.

Basic Information

Product Name	tert-Butyl Bromoacetate-13C
CAS No.	1173022-29-1
Molecular Formula	C6H1113CO2Br
Molecular Weight	195.06 g/mol (for 13C1)
Synonyms	Bromoacetic-1-13C acid tert-butyl ester; 2-Bromoacetic-1-13C acid 1,1-dimethylethyl ester; tert-Butyl 2-bromoacetate-1-13C; (13C)tert-Butyl bromoacetate; 1,1-Dimethylethyl bromoacetate-1-13C; Bromoacetic acid-1-13C tert-butyl ester; t-Butyl bromoacetate-13C; 2-Bromo-2-oxoethyl-1-13C tert-butyl carbonate (common misnomer)
EINECS	Contact for details

Quality Control

Our tert-Butyl Bromoacetate-13C is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing to ensure high isotopic and chemical purity, meeting the stringent requirements for research and development. Certificates of Analysis (COA) are provided, detailing specifications for isotopic enrichment, chemical purity (by GC/HPLC), and identity confirmation (by NMR, IR).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Isotopic Enrichment (13C)	≥ 99 atom %
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.