Description

3,3-Dimethyl-3H-Spiro[Isobenzofuran-1,4'-Piperidine] Hydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS number 1172717-60-0. This spirocyclic compound is a critical building block in modern medicinal chemistry, valued for its unique structural framework that enables the synthesis of complex bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, particularly within central nervous system (CNS) and oncology drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) for investigational new drugs.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• CNS Drug Development: Employed in the research and development of potential therapeutics targeting neurological disorders.
• Oncological Research: Serves as a building block for novel small-molecule candidates in cancer therapy research.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for advanced organic synthesis and pharmacological studies.

Basic Information

Product Name	3,3-Dimethyl-3H-Spiro[Isobenzofuran-1,4'-Piperidine] Hydrochloride
CAS No.	1172717-60-0
Molecular Formula	C15H20ClNO
Molecular Weight	265.78 g/mol
Synonyms	3,3-Dimethyl-3H-spiro[2-benzofuran-1,4'-piperidine] hydrochloride; 3H-Spiro[isobenzofuran-1,4'-piperidine], 3,3-dimethyl-, hydrochloride; 3,3-Dimethylspiro[isobenzofuran-1(3H),4'-piperidine] hydrochloride; Spiro[isobenzofuran-1(3H),4'-piperidine], 3,3-dimethyl-, hydrochloride; 1172717-60-0; CAS 1172717-60-0
EINECS	Contact for details

Quality Control

Our 3,3-Dimethyl-3H-Spiro[Isobenzofuran-1,4'-Piperidine] Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring the material meets the stringent requirements for pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to exclude moisture and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.