Description

6-n-Benzyl-2-Chloro-5,6,7,8-Tetrahydro-1,6-Naphthyridine Hcl is a high-purity organic compound that serves as a critical pharmaceutical intermediate and a versatile building block in advanced organic synthesis. Its value lies in its functionalized naphthyridine core, which is essential for constructing complex molecules with targeted biological activity. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Active Pharmaceutical Ingredient (API) Development: Used in the research and process development of new therapeutic agents.
• Agrochemical Synthesis: Serves as a precursor in the creation of advanced pesticides and herbicides.
• Fine Chemical Manufacturing: Employed in the production of specialty chemicals, dyes, and complex ligands for catalysis.
• Academic & Contract Research: A valuable reagent for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and CRO laboratories.
• Chemical Biology Probe Development: Used to create molecular tools for studying biological pathways and target validation.

Basic Information

Product Name	6-n-Benzyl-2-Chloro-5,6,7,8-Tetrahydro-1,6-Naphthyridine Hydrochloride
CAS No.	1172576-12-3
Molecular Formula	C15H16ClN2•HCl
Molecular Weight	297.21 g/mol (for free base: 261.76 g/mol)
Synonyms	2-Chloro-6-benzyl-5,6,7,8-tetrahydro-1,6-naphthyridine hydrochloride; 6-Benzyl-2-chloro-5,6,7,8-tetrahydro-1,6-naphthyridine HCl; 1,6-Naphthyridine, 2-chloro-5,6,7,8-tetrahydro-6-(phenylmethyl)-, hydrochloride (1:1); 1172576-12-3; 6-Benzyl-2-chloro-5,6,7,8-tetrahydro-1,6-naphthyridine monohydrochloride; 2-Chloro-6-(phenylmethyl)-5,6,7,8-tetrahydro-1,6-naphthyridine hydrochloride
EINECS	Contact for details

Quality Control

Our 6-n-Benzyl-2-Chloro-5,6,7,8-Tetrahydro-1,6-Naphthyridine Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance with cGMP and ICH Q7 guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.