Description

2-Azaspiro[3.3]Heptane-6-Carboxylic Acid, Hydrochloride (1:1) is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel drug candidates, particularly those targeting the central nervous system. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in CNS drug discovery.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its constrained spirocyclic structure.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a potential linker or component in the design of bifunctional degrader molecules.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds for preclinical and clinical trials.

Basic Information

Product Name	2-Azaspiro[3.3]Heptane-6-Carboxylic Acid, Hydrochloride (1:1)
CAS No.	1172252-57-1
Molecular Formula	C7H11NO2 • HCl
Molecular Weight	177.63 g/mol
Synonyms	6-Carboxy-2-azaspiro[3.3]heptane hydrochloride; 2-Azaspiro[3.3]heptane-6-carboxylic acid hydrochloride; 2-Azaspiro[3.3]heptane-6-carboxylic acid HCl; Azaspiroheptane carboxylic acid hydrochloride; 6-(Carboxy)-2-azaspiro[3.3]heptane hydrochloride; 1172252-57-1; 2-Azaspiro[3.3]heptane-6-carboxylic acid, hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Azaspiro[3.3]Heptane-6-Carboxylic Acid, Hydrochloride (1:1) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.