Description

5-Bromo[1,2,4]Triazolo[4,3-A]Pyridine is a high-value brominated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because it serves as a critical precursor for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. Pharmaceutical researchers, agrochemical developers, and material scientists need this specific intermediate for its unique reactivity profile, which enables the introduction of the bromo-triazolopyridine moiety into target molecules to modulate their biological activity and physical properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the heterocyclic core contributes to biological efficacy.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as ligands for OLEDs or charge-transport molecules.
• Chemical Biology Probes: Serves as a building block for creating labeled compounds or probes used in biochemical and diagnostic assays.
• Academic & Contract Research: Utilized in universities and CROs for methodological development and exploration of new chemical spaces.
• Catalyst Ligand Precursor: Can be functionalized to create novel ligands for transition metal catalysis.

Basic Information

Product Name	5-Bromo[1,2,4]Triazolo[4,3-A]Pyridine
CAS No.	1172085-67-4
Molecular Formula	C6H4BrN3
Molecular Weight	198.02 g/mol
Synonyms	5-Bromo[1,2,4]triazolo[4,3-a]pyridine; 5-Bromo-1,2,4-triazolo[4,3-a]pyridine; 5-Bromo-[1,2,4]triazolo[4,3-a]pyridine; 1172085-67-4; 5-Bromotriazolopyridine; [1,2,4]Triazolo[4,3-a]pyridine, 5-bromo-; 5-Bromo-s-triazolo[4,3-a]pyridine
EINECS	Contact for details

Quality Control

Our 5-Bromo[1,2,4]Triazolo[4,3-A]Pyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 1.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.