Description

1H-Pyrrolo[2,3-B]Pyridine, 5-Bromo-4-Fluoro-3-Nitro- is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its value lies in its unique halogenated and nitro-substituted structure, which provides multiple reactive sites for constructing complex molecular architectures. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery and synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, antiviral agents, and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated heterocyclic core for bioactivity.
• Material Science: Serves as a building block for creating functional organic materials, such as organic semiconductors or ligands for metal-organic frameworks (MOFs).
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring complex, multi-step functionalization of the pyrrolopyridine scaffold.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine, 5-Bromo-4-Fluoro-3-Nitro-
CAS No.	1172068-33-5
Molecular Formula	C7H3BrFN3O2
Molecular Weight	259.02 g/mol
Synonyms	5-Bromo-4-fluoro-3-nitro-1H-pyrrolo[2,3-b]pyridine; 5-Bromo-4-fluoro-3-nitropyrazolo[3,4-b]pyridine (alternative ring numbering); 5-Bromo-4-fluoro-3-nitro-7-azaindole; 5-Bromo-4-fluoro-3-nitro-1H-7-azaindole; 1H-Pyrrolo[2,3-b]pyridine, 5-bromo-4-fluoro-3-nitro-; 1172068-33-5; 5-Br-4-F-3-NO2-7-azaindole
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine, 5-Bromo-4-Fluoro-3-Nitro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown powder or crystalline solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.