Description

1H-Pyrrolo[2,3-B]Pyridine, 5-Bromo-4-Fluoro- is a high-value halogenated heterocyclic building block, specifically a bromo-fluoro substituted azaindole derivative, with the CAS number 1172067-95-6. This compound is critically important for medicinal chemistry and pharmaceutical research, serving as a versatile scaffold for the synthesis of novel drug candidates. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for constructing complex molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR).
• Agrochemical Development: Serves as a precursor for creating novel active ingredients with potential herbicidal or insecticidal properties.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target validation.
• Material Science: Potential precursor for organic electronic materials due to its fused heterocyclic structure.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process scale-up.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine, 5-Bromo-4-Fluoro-
CAS No.	1172067-95-6
Molecular Formula	C7H4BrFN2
Molecular Weight	215.03 g/mol
Synonyms	5-Bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridine; 4-Fluoro-5-bromo-1H-pyrrolo[2,3-b]pyridine; 5-Bromo-4-fluoro-7-azaindole; 4-Fluoro-5-bromo-7-azaindole; 1H-Pyrrolo[2,3-b]pyridine, 5-bromo-4-fluoro-; 5-Bromo-4-fluoro-1H-7-azaindole; 7-Azaindole, 5-bromo-4-fluoro-
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine, 5-Bromo-4-Fluoro- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) are available for every batch upon request, detailing all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.