Description

n-(6-Bromo-2-((tert-Butyldimethylsilyloxy)Methyl)-Furo[3,2-B]Pyridin-7-Yl)Pivalamide is a high-purity, advanced pharmaceutical intermediate with the CAS number 1171920-45-8. This compound is specifically designed for use in the synthesis of complex active pharmaceutical ingredients (APIs), offering a critical building block for medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel drug candidates, particularly in oncology and antiviral research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop new therapeutic molecules.
• API Synthesis: Serves as a crucial building block in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs).
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and development services for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for cutting-edge research in heterocyclic and organosilicon chemistry.

Basic Information

Product Name	n-(6-Bromo-2-((tert-Butyldimethylsilyloxy)Methyl)-Furo[3,2-B]Pyridin-7-Yl)Pivalamide
CAS No.	1171920-45-8
Molecular Formula	C20H29BrN2O3Si
Molecular Weight	453.45 g/mol
Synonyms	7-Pivalamido-6-bromo-2-((tert-butyldimethylsilyloxy)methyl)furo[3,2-b]pyridine; 6-Bromo-2-((tert-butyldimethylsilyloxy)methyl)-7-pivalamidofuro[3,2-b]pyridine; 1171920-45-8; TBDMS-protected bromofuropyridine pivalamide; Pivalamide, N-[6-bromo-2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]furo[3,2-b]pyridin-7-yl]-; N-(6-Bromo-2-(((tert-butyldimethylsilyl)oxy)methyl)furo[3,2-b]pyridin-7-yl)pivalamide
EINECS	Contact for details

Quality Control

Our n-(6-Bromo-2-((tert-Butyldimethylsilyloxy)Methyl)-Furo[3,2-B]Pyridin-7-Yl)Pivalamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.