Description

2-((tert-Butyldimethylsilyloxy)Methyl)-6-Iodofuro[3,2-B]Pyridine CAS NO 1171920-30-1 is a high-value, multi-functional heterocyclic building block featuring a protected hydroxymethyl group and a reactive iodine substituent. This compound is engineered to serve as a critical intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of new active ingredients for crop protection products.
• Material Science Research: Serves as a precursor for organic electronic materials and functional polymers.
• Cross-Coupling Reactions: The iodine atom facilitates versatile palladium-catalyzed cross-coupling (e.g., Suzuki, Sonogashira) for carbon-carbon bond formation.
• Medicinal Chemistry SAR Studies: Enables the exploration of structure-activity relationships by allowing modular derivatization at multiple sites.
• Chemical Biology Probes: Useful for synthesizing labeled compounds or probes for target identification and validation.

Basic Information

Product Name	2-((tert-Butyldimethylsilyloxy)Methyl)-6-Iodofuro[3,2-B]Pyridine
CAS No.	1171920-30-1
Molecular Formula	C15H22INO2Si
Molecular Weight	403.34 g/mol
Synonyms	6-Iodo-2-(((tert-butyldimethylsilyl)oxy)methyl)furo[3,2-b]pyridine; 2-(((tert-Butyldimethylsilyl)oxy)methyl)-6-iodofuro[3,2-b]pyridine; TBDMS-protected 6-iodofuro[3,2-b]pyridine methanol; 6-Iodo-2-((TBDMS-oxymethyl))furo[3,2-b]pyridine; Furo[3,2-b]pyridine, 6-iodo-2-(((1,1-dimethylethyl)dimethylsilyl)oxy)methyl]-; 1171920-30-1
EINECS	Contact for details

Quality Control

Our 2-((tert-Butyldimethylsilyloxy)Methyl)-6-Iodofuro[3,2-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.