Description

n-(2-Bromo-5-Methoxypyridin-3-Yl)Pivalamide is a high-purity, advanced pharmaceutical intermediate characterized by its brominated pyridine core and pivalamide protecting group. This compound is crucial for medicinal chemistry research and development, serving as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of potential drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic programs.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Agrochemical Synthesis: Serves as a precursor in the development of new pesticides and herbicides, leveraging its halogenated heterocyclic structure.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for specialized, high-value chemical products.
• Chemical Biology Probes: Can be utilized to develop molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	n-(2-Bromo-5-Methoxypyridin-3-Yl)Pivalamide
CAS No.	1171920-11-8
Molecular Formula	C11H15BrN2O2
Molecular Weight	287.15 g/mol
Synonyms	2-Bromo-5-methoxy-N-(2,2-dimethylpropanoyl)pyridin-3-amine; Pivalamide, N-(2-bromo-5-methoxy-3-pyridinyl)-; 3-Amino-2-bromo-5-methoxypyridine pivalamide; 1171920-11-8; N-(2-Bromo-5-methoxypyridin-3-yl)-2,2-dimethylpropanamide; tert-Butylamide of 2-bromo-5-methoxy-3-aminopyridine
EINECS	Contact for details

Quality Control

Our n-(2-Bromo-5-Methoxypyridin-3-Yl)Pivalamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.