Description

tert-Butyl 3-((3-Iodopyridin-4-Yloxy)Methyl)-Pyrrolidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a unique molecular scaffold combining a protected pyrrolidine ring with a substituted pyridine moiety. This compound is of significant value for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in the development of targeted therapies, particularly in areas requiring complex heterocyclic structures.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis to explore new chemical entities.
• API Development: Serves as a critical building block in the development and scale-up processes for new active pharmaceutical ingredients.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying biological pathways and target validation due to its functionalized structure.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Academic Research: Employed in university and institutional labs for advanced organic synthesis projects and methodological studies.

Basic Information

Product Name	tert-Butyl 3-((3-Iodopyridin-4-Yloxy)Methyl)-Pyrrolidine-1-Carboxylate
CAS No.	1171920-04-9
Molecular Formula	C15H21IN2O3
Molecular Weight	404.25 g/mol
Synonyms	1-Boc-3-((3-iodopyridin-4-yloxy)methyl)pyrrolidine; 1-(tert-Butoxycarbonyl)-3-[(3-iodo-4-pyridinyloxy)methyl]pyrrolidine; tert-Butyl 3-[(3-iodopyridin-4-yl)oxymethyl]pyrrolidine-1-carboxylate; 3-((3-Iodopyridin-4-yloxy)methyl)pyrrolidine-1-carboxylic acid tert-butyl ester; 1-Boc-3-((3-iodo-4-pyridyloxy)methyl)pyrrolidine; Pyrrolidine-1-carboxylic acid, 3-[(3-iodo-4-pyridinyloxy)methyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-((3-Iodopyridin-4-Yloxy)Methyl)-Pyrrolidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards where applicable, ensuring material integrity for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.