Description

n-(2-Bromo-5-Cyanopyridin-3-Yl)Pivalamide is a high-purity, multi-functional pyridine derivative building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is needed by R&D chemists and process development scientists for constructing active pharmaceutical ingredients (APIs), agrochemicals, and functional materials, where its bromo and cyano substituents offer versatile sites for further functionalization.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic research.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic systems for cross-coupling and other transition metal-catalyzed reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials and functional polymers due to its electron-withdrawing groups.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	n-(2-Bromo-5-Cyanopyridin-3-Yl)Pivalamide
CAS No.	1171920-02-7
Molecular Formula	C11H12BrN3O
Molecular Weight	282.14 g/mol
Synonyms	2-Bromo-5-cyano-N-(2,2-dimethylpropanoyl)pyridin-3-amine; Pivalamide, N-(2-bromo-5-cyano-3-pyridinyl)-; 3-Amino-2-bromo-5-cyanopyridine pivalamide; 1171920-02-7; N-(2-Bromo-5-cyanopyridin-3-yl)-2,2-dimethylpropanamide; tert-Butylcarboxamide derivative of 3-amino-2-bromo-5-cyanopyridine
EINECS	Contact for details

Quality Control

Our n-(2-Bromo-5-Cyanopyridin-3-Yl)Pivalamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.