Description

n-(2-Bromo-5-(Dimethoxymethyl)Pyridin-3-Yl)-Pivalamide is a high-purity, advanced pharmaceutical intermediate characterized by its unique halogenated pyridine and pivalamide structure. This compound is of significant value for enabling complex molecular transformations in the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily needed by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key building block in the research and commercial synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced crop protection agents and herbicides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for electronic materials and polymers.
• Cross-Coupling Reactions: The bromine substituent makes it a valuable substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Chemical Biology Probes: Used to develop molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	n-(2-Bromo-5-(Dimethoxymethyl)Pyridin-3-Yl)-Pivalamide
CAS No.	1171919-93-9
Molecular Formula	C13H19BrN2O3
Molecular Weight	331.21 g/mol
Synonyms	2-Bromo-5-(dimethoxymethyl)-N-(2,2-dimethylpropanoyl)pyridin-3-amine; Pivalamide, N-[2-bromo-5-(dimethoxymethyl)-3-pyridinyl]-; 3-Amino-2-bromo-5-(dimethoxymethyl)pyridine Pivalamide; N-(2-Bromo-5-(dimethoxymethyl)-3-pyridinyl)-2,2-dimethylpropanamide; 1171919-93-9; tert-Butylamide derivative of bromo-dimethoxymethyl-pyridine
EINECS	Contact for details

Quality Control

Our n-(2-Bromo-5-(Dimethoxymethyl)Pyridin-3-Yl)-Pivalamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support development and commercial projects requiring compliance with cGMP, ICH Q7, and other relevant pharmaceutical guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.