Description

n-(2-Bromo-5-(Hydroxymethyl)Pyridin-3-Yl)-Pivalamide is a high-purity, advanced pharmaceutical intermediate characterized by its brominated pyridine core and pivalamide protecting group. This compound matters for its critical role in the synthesis of complex active pharmaceutical ingredients (APIs), where it serves as a key building block to introduce specific molecular functionality. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries engaged in developing novel small-molecule therapeutics and crop protection agents.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its halogenated heterocyclic structure.
• Chemical Research & Development: Serves as a versatile precursor for organic synthesis, enabling the exploration of new chemical entities in academic and industrial R&D labs.
• API Manufacturing: Integrated into scaled-up production processes for Active Pharmaceutical Ingredients requiring this specific bromopyridine derivative.
• Ligand and Catalyst Development: Potential use in creating specialized ligands for metal-catalyzed coupling reactions, common in modern synthetic chemistry.

Basic Information

Product Name	n-(2-Bromo-5-(Hydroxymethyl)Pyridin-3-Yl)-Pivalamide
CAS No.	1171919-92-8
Molecular Formula	C11H15BrN2O2
Molecular Weight	287.15 g/mol
Synonyms	2-Bromo-5-(hydroxymethyl)-N-(2,2-dimethylpropanoyl)pyridin-3-amine; Pivalamide, N-[2-bromo-5-(hydroxymethyl)-3-pyridinyl]-; 3-Amino-2-bromo-5-(hydroxymethyl)pyridine Pivalamide; 1171919-92-8; N-(2-Bromo-5-(hydroxymethyl)pyridin-3-yl)-2,2-dimethylpropanamide
EINECS	Contact for details

Quality Control

Our n-(2-Bromo-5-(Hydroxymethyl)Pyridin-3-Yl)-Pivalamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure compliance with stringent industry standards. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.