Description

2,3-Dimethoxy-5-((Trimethylsilyl)Ethynyl)Pyridine is a specialized organosilicon pyridine derivative that serves as a key synthetic intermediate. Its molecular architecture, featuring both electron-donating methoxy groups and a reactive ethynylsilane moiety, makes it a valuable building block for constructing complex molecular frameworks. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and advanced materials sectors.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting neurological and oncological pathways.
• Ligand Synthesis: Used in the preparation of sophisticated ligands for catalysis, including those for cross-coupling and C-H activation reactions.
• Material Science Building Block: Employed in the development of organic electronic materials, such as molecular wires, semiconductors, and light-emitting components.
• Agrochemical Research: Serves as an intermediate in the discovery and development of novel crop protection agents and herbicides.
• Academic & R&D: A valuable reagent for methodological development in organic synthesis and medicinal chemistry research within university and corporate laboratories.

Basic Information

Product Name	2,3-Dimethoxy-5-((Trimethylsilyl)Ethynyl)Pyridine
CAS No.	1171919-88-2
Molecular Formula	C₁₂H₁₇NO₂Si
Molecular Weight	235.36 g/mol
Synonyms	5-[(Trimethylsilyl)ethynyl]-2,3-dimethoxypyridine; 2,3-Dimethoxy-5-(2-trimethylsilylethynyl)pyridine; Pyridine, 5-[(trimethylsilyl)ethynyl]-2,3-dimethoxy-; 5-(Trimethylsilylethynyl)-2,3-dimethoxypyridine; 2,3-Dimethoxy-5-(trimethylsilylethynyl)pyridine; TMS-Ethynyl Dimethoxypyridine
EINECS	Contact for details

Quality Control

Our 2,3-Dimethoxy-5-((Trimethylsilyl)Ethynyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.