Description

4-Amino-2-Iodopyridin-3-Ol is a halogenated aminopyridinol derivative, a versatile and high-value building block in advanced organic synthesis. Its unique structure, featuring both an amino and an iodo substituent on the pyridine ring, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and insecticides with specific modes of action.
• Ligand and Catalyst Development: Used to create novel chelating ligands and organocatalysts for asymmetric synthesis and metal-catalyzed cross-coupling reactions.
• Material Science Research: Intermediate in the production of functional organic materials, such as organic semiconductors and liquid crystals.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes and tags used in biochemical and diagnostic research.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects and process development.

Basic Information

Product Name	4-Amino-2-Iodopyridin-3-Ol
CAS No.	1171919-81-5
Molecular Formula	C5H5IN2O
Molecular Weight	236.01 g/mol
Synonyms	3-Hydroxy-2-iodo-4-aminopyridine; 4-Amino-3-hydroxy-2-iodopyridine; 2-Iodo-4-aminopyridin-3-ol; 4-Amino-2-iodo-3-pyridinol; 4-Amino-2-iodo-3-hydroxypyridine; 1171919-81-5; 4-Amino-2-iodopyridin-3-ol
EINECS	Contact for details

Quality Control

Every batch of 4-Amino-2-Iodopyridin-3-Ol is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure product integrity and traceability. Our standard quality commitment includes HPLC purity ≥95% (with higher grades available), identity confirmation via spectroscopic methods, and stringent control of residual solvents and heavy metals. A detailed Certificate of Analysis (COA) is provided with each shipment, and we support customer audits and regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.