Description

5-((tert-Butyldimethylsilyloxy)Methyl)-2,3-Dimethoxypyridine is a high-purity, protected pyridine derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in the tert-butyldimethylsilyl (TBDMS) protecting group, which provides exceptional stability for sensitive functional group manipulations under a wide range of reaction conditions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the protected hydroxymethyl group enables selective derivatization.
• Ligand and Catalyst Preparation: Serves as a precursor for nitrogen-containing ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the creation of functionalized polymers and organic electronic materials.
• Academic & Process R&D: A valuable reagent for methodological development in organic synthesis and scale-up process optimization.

Basic Information

Product Name	5-((tert-Butyldimethylsilyloxy)Methyl)-2,3-Dimethoxypyridine
CAS No.	1171919-74-6
Molecular Formula	C14H25NO3Si
Molecular Weight	283.44 g/mol
Synonyms	2,3-Dimethoxy-5-(((tert-butyldimethylsilyl)oxy)methyl)pyridine; 5-(((tert-Butyldimethylsilyl)oxy)methyl)-2,3-dimethoxypyridine; 2,3-Dimethoxy-5-((TBDMS-oxy)methyl)pyridine; 5-(TBDMS-oxymethyl)-2,3-dimethoxypyridine; 5-(Hydroxymethyl)-2,3-dimethoxypyridine TBDMS ether; TBDMS-protected 5-hydroxymethyl-2,3-dimethoxypyridine; Pyridine, 5-[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-2,3-dimethoxy-
EINECS	Contact for details

Quality Control

Our 5-((tert-Butyldimethylsilyloxy)Methyl)-2,3-Dimethoxypyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.