Description

5-Bromo-6-Methyl-2-(Methylamino)-4-(Trifluoromethyl)Nicotinonitrile is a high-value, multi-functional heterocyclic building block designed for advanced synthetic chemistry. This compound matters for its unique trifluoromethyl and bromo substituents, which are critical for modulating the lipophilicity, metabolic stability, and binding affinity of target molecules in pharmaceutical discovery. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Development: Used to construct advanced pyridine-based scaffolds for new herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a specialized monomer or additive in the development of functional polymers and organic electronic materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	5-Bromo-6-Methyl-2-(Methylamino)-4-(Trifluoromethyl)Nicotinonitrile
CAS No.	1171919-20-2
Molecular Formula	C9H7BrF3N3
Molecular Weight	294.07 g/mol
Synonyms	2-(Methylamino)-5-bromo-6-methyl-4-(trifluoromethyl)nicotinonitrile; 5-Bromo-6-methyl-2-(methylamino)-4-(trifluoromethyl)pyridine-3-carbonitrile; 4-(Trifluoromethyl)-5-bromo-6-methyl-2-(methylamino)nicotinonitrile; 1171919-20-2; Nicotinonitrile, 5-bromo-6-methyl-2-(methylamino)-4-(trifluoromethyl)-; 2-Methylamino-5-bromo-6-methyl-4-trifluoromethyl-3-cyanopyridine
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-6-Methyl-2-(Methylamino)-4-(Trifluoromethyl)Nicotinonitrile is produced under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the rigorous standards required for research and development. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profile by HPLC, NMR, and MS is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.