Description

1-[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]-4-Piperidinecarbonitrile is a high-purity, advanced pharmaceutical intermediate featuring a unique pyridine-piperidine scaffold. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with targeted biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in the areas of central nervous system (CNS) and anti-infective drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially those targeting neurological receptors.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging its halogenated heterocyclic structure.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and protein-ligand interactions.
• Organic Synthesis Building Block: Provides a versatile scaffold for constructing complex molecules in academic and industrial R&D settings.
• Material Science Research: Investigated as a potential monomer or additive for creating specialty polymers with specific electronic or physical properties.

Basic Information

Product Name	1-[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]-4-Piperidinecarbonitrile
CAS No.	1171918-97-0
Molecular Formula	C12H9ClF3N3
Molecular Weight	287.67 g/mol
Synonyms	4-Piperidinecarbonitrile, 1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-; 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperidine-4-carbonitrile; 2-(4-Cyanopiperidin-1-yl)-3-chloro-5-(trifluoromethyl)pyridine; 3-Chloro-5-(trifluoromethyl)-2-(4-cyanopiperidin-1-yl)pyridine; 1171918-97-0; CAS 1171918-97-0
EINECS	Contact for details

Quality Control

Our 1-[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]-4-Piperidinecarbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliable supply for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.