Description

2-Chloro-4,6-Diiodo-3-Pyridinol is a halogenated pyridine derivative that serves as a versatile and highly functionalized chemical building block. Its unique structure, featuring both chloro and iodo substituents, makes it a critical intermediate for synthesizing complex molecules in advanced research and development. This compound is primarily sought by pharmaceutical, agrochemical, and specialty chemical manufacturers for applications in drug discovery, ligand synthesis, and the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents, herbicides, and fungicides due to its reactive halogen sites.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Sonogashira) and nucleophilic substitution reactions to introduce the pyridinol core into complex structures.
• Material Science Research: Potential intermediate in the synthesis of organic electronic materials and metal-organic frameworks (MOFs).
• Bioconjugation & Probe Chemistry: Useful for modifying biomolecules or creating fluorescent probes in life science research.

Basic Information

Product Name	2-Chloro-4,6-Diiodo-3-Pyridinol
CAS No.	1171918-88-9
Molecular Formula	C5H2ClI2NO
Molecular Weight	385.29 g/mol
Synonyms	3-Pyridinol, 2-chloro-4,6-diiodo-; 2-Chloro-4,6-diiodopyridin-3-ol; 4,6-Diiodo-2-chloro-3-hydroxypyridine; 2-Chloro-4,6-diiodo-3-pyridinone; 2-Chloro-4,6-diiodopyridin-3(2H)-one (tautomer)
EINECS	Contact for details

Quality Control

Our 2-Chloro-4,6-Diiodo-3-Pyridinol is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR), to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep away from strong acids/bases and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.