Description

n-(5-Bromopyridin-3-Yl)Propionamide is a high-purity brominated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a functionalized scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific bromine-substituted pyridine motifs into their target structures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides where the bromopyridine moiety is a core structural element.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and material science applications.
• Chemical Biology Probes: Serves as a building block for creating molecular probes to study biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Academic & R&D: Utilized in university and institutional laboratories for methodological development and novel compound library generation.

Basic Information

Product Name	n-(5-Bromopyridin-3-Yl)Propionamide
CAS No.	1171897-14-5
Molecular Formula	C8H9BrN2O
Molecular Weight	229.08 g/mol
Synonyms	5-Bromo-N-(pyridin-3-yl)propanamide; 3-(5-Bromopyridin-3-ylamino)propanoic acid amide; 5-Bromo-3-propionamidopyridine; N-(5-Bromo-3-pyridinyl)propionamide; Propionamide, N-(5-bromo-3-pyridinyl)-; 1171897-14-5; 5-Bromonicotinamide propionyl derivative
EINECS	Contact for details

Quality Control

Our n-(5-Bromopyridin-3-Yl)Propionamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.