Description

4-Acetylamino-n-[5-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)Pyridin-3-Yl]Butyramide is a high-value, functionalized pyridine-boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and plant growth regulators with specific activity profiles.
• Material Science Research: Used in the development of organic electronic materials, such as OLEDs and conductive polymers, due to its boronic ester functionality.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and activity-based protein profiling (ABPP) reagents.
• Ligand & Catalyst Development: Serves as a starting material for synthesizing novel bidentate ligands and organometallic catalysts.
• Custom Synthesis & Contract Manufacturing: A vital intermediate for custom synthesis houses serving the life sciences industry.

Basic Information

Product Name	4-Acetylamino-n-[5-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)Pyridin-3-Yl]Butyramide
CAS No.	1171891-25-0
Molecular Formula	C17H26BN3O4
Molecular Weight	347.22 g/mol
Synonyms	4-Acetylamino-N-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl)butyramide; 5-(4-Acetylamino-n-butyramido)pyridine-3-boronic acid pinacol ester; 3-Pyridinebutanamide, N-[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-pyridinyl]-4-(acetylamino)-; CAS 1171891-25-0; 4-Acetamido-N-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl)butyramide
EINECS	Contact for details

Quality Control

Our 4-Acetylamino-n-[5-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)Pyridin-3-Yl]Butyramide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.