Description

1,3-Dimethyl-6-(1-Methylpyrazol-4-Yl)Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This heterocyclic carboxylic acid derivative is a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly kinase inhibitors. It is primarily sought after by pharmaceutical R&D departments and fine chemical manufacturers engaged in the development of targeted therapies for oncology and inflammatory diseases.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of protein kinase inhibitors for targeted cancer therapies.
• Biochemical Research: Used as a core scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and hit-to-lead optimization.
• API Development: Serves as a critical building block in the multi-step synthesis of complex drug candidates under Good Manufacturing Practice (GMP) conditions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for exploring new heterocyclic chemistry and drug discovery pathways.

Basic Information

Product Name	1,3-Dimethyl-6-(1-Methylpyrazol-4-Yl)Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid
CAS No.	1171848-55-7
Molecular Formula	C15H15N5O2
Molecular Weight	297.31 g/mol
Synonyms	1,3-Dimethyl-6-(1-methyl-1H-pyrazol-4-yl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; 6-(1-Methyl-1H-pyrazol-4-yl)-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; 1171848-55-7; Pyrazolo[3,4-b]pyridine-4-carboxylic acid, 1,3-dimethyl-6-(1-methyl-1H-pyrazol-4-yl)-; 1H-Pyrazolo[3,4-b]pyridine-4-carboxylic acid, 1,3-dimethyl-6-(1-methyl-1H-pyrazol-4-yl)-
EINECS	Contact for details

Quality Control

Our production of 1,3-Dimethyl-6-(1-Methylpyrazol-4-Yl)Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for sensitive pharmaceutical applications. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.