Description

[6-(1-Ethyl-1H-Pyrazol-3-Yl)-3-Methyl-1H-Pyrazolo[3,4-B]Pyridin-1-Yl]Acetic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of targeted therapies, particularly in oncology and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel drug candidates, especially kinase inhibitors.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic molecules.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.
• Biochemical Research: May be utilized as a tool compound or ligand in biochemical assays to study specific biological pathways and protein interactions.
• Academic Research: Employed in university and institutional labs for cutting-edge research in organic synthesis and drug discovery methodologies.

Basic Information

Product Name	[6-(1-Ethyl-1H-Pyrazol-3-Yl)-3-Methyl-1H-Pyrazolo[3,4-B]Pyridin-1-Yl]Acetic Acid
CAS No.	1171776-92-3
Molecular Formula	C16H17N5O2
Molecular Weight	311.34 g/mol
Synonyms	1H-Pyrazolo[3,4-b]pyridine-1-acetic acid, 6-(1-ethyl-1H-pyrazol-3-yl)-3-methyl-; (6-(1-Ethyl-1H-pyrazol-3-yl)-3-methyl-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid; 1171776-92-3; UNII-9K6K7C8R2I; 9K6K7C8R2I; SCHEMBL23346879; DTXSID60664688; BDBM50391057
EINECS	Contact for details

Quality Control

Every batch of [6-(1-Ethyl-1H-Pyrazol-3-Yl)-3-Methyl-1H-Pyrazolo[3,4-B]Pyridin-1-Yl]Acetic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the identity, purity, and consistency required for pharmaceutical R&D and scale-up. A detailed Certificate of Analysis (COA) including results from HPLC, NMR, and mass spectrometry is supplied with each shipment to guarantee compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.