Description

2-(Pyrrolidin-1-Yl)Pyridine-3-Carbonitrile Hydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS number 1171498-25-1. This compound is critical for medicinal chemistry research and the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly in kinase inhibitor research.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Synthesis: Serves as a versatile precursor for constructing heterocyclic compounds with potential biological activity.
• Biochemical Research: Employed in the development of molecular probes and tool compounds for biological target validation.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional laboratories for exploratory organic synthesis and methodology development.

Basic Information

Product Name	2-(Pyrrolidin-1-Yl)Pyridine-3-Carbonitrile Hydrochloride
CAS No.	1171498-25-1
Molecular Formula	C10H12N3·HCl
Molecular Weight	209.68 g/mol (Free base: 173.22 g/mol)
Synonyms	2-(1-Pyrrolidinyl)-3-pyridinecarbonitrile hydrochloride; 3-Cyano-2-(pyrrolidin-1-yl)pyridine hydrochloride; 2-Pyrrolidin-1-ylpyridine-3-carbonitrile HCl; 2-(Pyrrolidin-1-yl)nicotinonitrile hydrochloride; 1171498-25-1; 2-(N-Pyrrolidino)pyridine-3-carbonitrile hydrochloride
EINECS	Contact for details

Quality Control

Our 2-(Pyrrolidin-1-Yl)Pyridine-3-Carbonitrile Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or manufacturing specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.