Description

(4-Aminopiperidin-1-Yl)(Pyridin-4-Yl)Methanone Dihydrochloride is a high-purity, pharmaceutically relevant building block and intermediate. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel bioactive molecules. It is primarily sought by pharmaceutical, biotechnology, and fine chemical companies engaged in drug discovery programs targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop new chemical entities.
• Protease Inhibitor Development: Serves as a core scaffold or precursor in the design of protease inhibitors due to its aminopiperidine moiety.
• Kinase Inhibitor Synthesis: Employed in the construction of heterocyclic compounds targeting various kinase enzymes.
• Chemical Biology Probes: Utilized to create tool compounds for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production.

Basic Information

Product Name	(4-Aminopiperidin-1-Yl)(Pyridin-4-Yl)Methanone Dihydrochloride
CAS No.	1171497-43-0
Molecular Formula	C11H16Cl2N3O
Molecular Weight	277.17 g/mol
Synonyms	4-Pyridinyl(4-aminopiperidin-1-yl)methanone dihydrochloride; 1-(4-Pyridinecarbonyl)-4-piperidinamine dihydrochloride; (4-Aminopiperidin-1-yl)(4-pyridinyl)methanone hydrochloride (1:2); (4-Aminopiperidin-1-yl)(pyridin-4-yl)methanone HCl; 4-Aminopiperidine-1-carboxylic acid pyridin-4-yl ester dihydrochloride (tautomeric form); CAS 1171497-43-0
EINECS	Contact for details

Quality Control

Our (4-Aminopiperidin-1-Yl)(Pyridin-4-Yl)Methanone Dihydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry. Certificates of Analysis (COA) are available for every batch and supplied upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.