Description

1,9-Diazaspiro[5.5]Undecan-2-One Hydrochloride is a high-purity, advanced pharmaceutical intermediate and building block. This compound is valued for its rigid spirocyclic structure, which is crucial for modulating the biological activity and physicochemical properties of novel drug candidates. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and development of new therapeutic agents, particularly in central nervous system (CNS) and metabolic disorder research.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel small molecule drugs.
• Medicinal Chemistry Research: Used as a privileged scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Protease Inhibitor Development: The diazaspiro structure is relevant in the design of inhibitors for various enzymatic targets.
• Ligand Synthesis: Employed in the synthesis of complex ligands for biological targeting and diagnostic applications.
• Chemical Biology Probes: Serves as a core structure for creating probes to study biological pathways and protein function.
• Process Chemistry & Scale-Up: Supplied for route scouting, optimization, and pilot-scale synthesis under current Good Manufacturing Practice (cGMP) guidelines where required.

Basic Information

Item	Details
Product Name	1,9-Diazaspiro[5.5]Undecan-2-One Hydrochloride
CAS No.	1171417-47-2
Molecular Formula	C9H17ClN2O
Molecular Weight	204.70 g/mol
Synonyms	1,9-Diazaspiro[5.5]undecan-2-one, HCl; 2-Oxo-1,9-diazaspiro[5.5]undecane hydrochloride; 1,9-Diazaspiro[5.5]undecane-2-one hydrochloride; Spirocyclic Diamine Hydrochloride; CAS 1171417-47-2
EINECS	Contact for details

Quality Control

Every batch of 1,9-Diazaspiro[5.5]Undecan-2-One Hydrochloride is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to support your regulatory filings, including identity confirmation, purity assessment, and impurity profiling. A Certificate of Analysis (COA) detailing specifications and test results (e.g., by HPLC, NMR) is supplied with each shipment to ensure traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.