Description

1-(Methoxyacetyl)-1,2,3,4-Tetrahydroquinolin-7-Amine is a high-purity, advanced pharmaceutical intermediate characterized by its tetrahydroquinoline core structure. This compound matters for its critical role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated heterocyclic chemistry. Pharmaceutical R&D and manufacturing organizations need this material for developing new drug candidates, where consistent quality and reliable supply are paramount for successful process development and scale-up.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and production of novel drug molecules, particularly those targeting the central nervous system (CNS) and other therapeutic areas.
• Organic Synthesis Building Block: Used in complex multi-step organic syntheses to construct more elaborate molecular architectures due to its reactive amine and amide functional groups.
• Medicinal Chemistry Research: Employed in hit-to-lead optimization and structure-activity relationship (SAR) studies for new chemical entities in academic and industrial labs.
• Contract Manufacturing & Development (CDMO): Supplied to CDMOs for the cGMP production of clinical trial materials and commercial APIs for global markets.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	1-(Methoxyacetyl)-1,2,3,4-Tetrahydroquinolin-7-Amine
CAS No.	1171346-38-5
Molecular Formula	C12H16N2O2
Molecular Weight	220.27 g/mol
Synonyms	7-Amino-1-(methoxyacetyl)-1,2,3,4-tetrahydroquinoline; 1,2,3,4-Tetrahydroquinolin-7-amine, 1-(methoxyacetyl)-; 1-(Methoxyacetyl)-7-amino-1,2,3,4-tetrahydroquinoline; N-(7-Amino-1,2,3,4-tetrahydroquinolin-1-yl)-2-methoxyacetamide; 2-Methoxy-N-(7-amino-3,4-dihydro-2H-quinolin-1-yl)acetamide
EINECS	Contact for details

Quality Control

Our 1-(Methoxyacetyl)-1,2,3,4-Tetrahydroquinolin-7-Amine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to meet the stringent requirements of pharmaceutical development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.