Description

3-Carboxy-1-[(Pyridin-2-Yl)Methyl]Piperidine Dihydrochloride, 2-[(3-Carboxypiperidin-1-Yl)Methyl]Pyridine Dihydrochloride is a high-purity, pharmaceutically relevant intermediate characterized by its piperidine and pyridine core structures. This compound is critical for research and development in medicinal chemistry, serving as a key building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers requiring reliable, high-quality intermediates for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new molecular entities.
• Process Chemistry Development: Serves as a critical starting material or intermediate in scaling up API synthesis under GMP conditions.
• Chemical Biology Probes: Utilized in the development of tool compounds for target validation and biochemical pathway studies.
• Custom Synthesis: A versatile scaffold for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.
• Ligand Synthesis: Potential use in creating complex ligands for catalysis or metal-organic frameworks due to its chelating carboxylate and nitrogen donor sites.

Basic Information

Product Name	3-Carboxy-1-[(Pyridin-2-Yl)Methyl]Piperidine Dihydrochloride, 2-[(3-Carboxypiperidin-1-Yl)Methyl]Pyridine Dihydrochloride
CAS No.	1171204-54-8
Molecular Formula	C13H18N2O2 • 2HCl
Molecular Weight	323.21 g/mol (for dihydrochloride salt)
Synonyms	1-(Pyridin-2-ylmethyl)piperidine-3-carboxylic acid dihydrochloride; 2-[(3-Carboxypiperidin-1-yl)methyl]pyridine dihydrochloride; 3-Piperidinecarboxylic acid, 1-[(2-pyridinyl)methyl]-, dihydrochloride; 1-(2-Pyridylmethyl)-3-piperidinecarboxylic acid dihydrochloride; 3-Carboxy-1-(pyridin-2-ylmethyl)piperidinium chloride hydrochloride; 1171204-54-8; CAS 1171204-54-8
EINECS	Contact for details

Quality Control

Our 3-Carboxy-1-[(Pyridin-2-Yl)Methyl]Piperidine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation and moisture uptake. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm
Assay (Titration)	97.0% - 103.0% (on anhydrous basis)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.