Description

4-Pyridinecarboxylic Acid, 2-Chloro-6-(1,1-Dimethylethyl)- is a high-purity, synthetically valuable pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a carboxylic acid and a chloro-substituent adjacent to a bulky tert-butyl group, makes it an essential intermediate for creating complex molecules with tailored properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for creating libraries of compounds targeting specific enzymes or receptors.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the creation of organic semiconductors, metal-organic frameworks (MOFs), or other functional organic materials.
• Chemical Biology Probes: Useful for designing molecular probes and tags for studying biological processes due to its modifiable functional groups.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex intermediates.

Basic Information

Item	Details
Product Name	4-Pyridinecarboxylic Acid, 2-Chloro-6-(1,1-Dimethylethyl)-
CAS No.	1170999-92-4
Molecular Formula	C10H12ClNO2
Molecular Weight	213.66 g/mol
Synonyms	2-Chloro-6-tert-butylisonicotinic Acid; 2-Chloro-6-(tert-butyl)pyridine-4-carboxylic Acid; 2-Chloro-6-(1,1-dimethylethyl)-4-pyridinecarboxylic Acid; 6-tert-Butyl-2-chloroisonicotinic Acid; 4-Carboxy-2-chloro-6-tert-butylpyridine; 2-Chloro-6-tert-butyl-4-pyridinecarboxylic Acid; 2-Chloro-6-(tert-butyl)isonicotinic Acid
EINECS	Contact for details

Quality Control

Every batch of 4-Pyridinecarboxylic Acid, 2-Chloro-6-(1,1-Dimethylethyl)- is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting customer specifications and industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.