Description

n-(tert-Butyl)-1'H-Spiro[Piperidine-4,2'-Quinoxalin]-3'-Amine is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic piperidine-quinoxaline hybrid structure. This compound is of significant value for medicinal chemistry research and development, offering a sophisticated scaffold for the synthesis of novel bioactive molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization programs.
• Chemical Biology Probe Development: Employed in the creation of molecular probes to study biological pathways and protein function.
• Process Chemistry & Scale-Up: Supplied for route scouting, optimization, and pilot-scale production of active pharmaceutical ingredients (APIs).
• Contract Research & Manufacturing (CRO/CMO): A key material for organizations providing custom synthesis and development services.
• Academic Research: Used in university and institutional labs for exploratory synthetic chemistry and pharmacology projects.

Basic Information

Product Name	n-(tert-Butyl)-1'H-Spiro[Piperidine-4,2'-Quinoxalin]-3'-Amine
CAS No.	1170643-61-4
Molecular Formula	C16H24N4
Molecular Weight	272.39 g/mol
Synonyms	1'H-Spiro[piperidine-4,2'-quinoxalin]-3'-amine, N-(1,1-dimethylethyl)-; tert-Butylspiro[piperidine-4,2'-quinoxalin]-3'-amine; Spiro[piperidine-4,2'-quinoxalin]-3'-amine, N-tert-butyl-; 1170643-61-4; N-(tert-Butyl)spiro[piperidine-4,2'-quinoxalin]-3'-amine; 3'-Amino-N-tert-butylspiro[piperidine-4,2'-quinoxaline]; N-tert-Butyl-1'H-spiro[piperidine-4,2'-quinoxalin]-3'-amine
EINECS	Contact for details

Quality Control

Our n-(tert-Butyl)-1'H-Spiro[Piperidine-4,2'-Quinoxalin]-3'-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with full analytical data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.