Description

n-(Pyridin-3-Ylmethyl)Piperidine-4-Carboxamide Dihydrochloride is a high-purity chemical building block and pharmaceutical intermediate of significant commercial interest. This compound is valued for its role in the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and other therapeutic areas. It is primarily sought by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Serves as a critical starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme inhibition or receptor binding activities.
• Reference Standard: Utilized as an analytical standard for quality control and method validation in API manufacturing.
• Academic Research: Applied in university and institutional labs for synthetic organic chemistry and pharmacology studies.

Basic Information

Product Name	n-(Pyridin-3-Ylmethyl)Piperidine-4-Carboxamide Dihydrochloride
CAS No.	1170206-86-6
Molecular Formula	C13H20N4O • 2HCl
Molecular Weight	329.25 g/mol (free base: 248.33 g/mol)
Synonyms	1-(Pyridin-3-ylmethyl)piperidine-4-carboxamide dihydrochloride; 3-[(4-Carbamoylpiperidin-1-yl)methyl]pyridine dihydrochloride; N-(Pyridin-3-ylmethyl)isonipecotamide dihydrochloride; Piperidine-4-carboxamide, N-(3-pyridinylmethyl)-, dihydrochloride; UNII-7J8Q3K4A0P; 1170206-86-6; Amide, N-(3-pyridinylmethyl)-4-piperidinecarboxylic acid, dihydrochloride
EINECS	Contact for details

Quality Control

Our n-(Pyridin-3-Ylmethyl)Piperidine-4-Carboxamide Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.