Description

1,4-Piperidinedicarboxylic Acid, 4-Methyl-3-Oxo-, 1-(1,1-Dimethylethyl) 4-Ethyl Ester is a high-purity, synthetically valuable piperidine derivative used as a critical building block in advanced organic synthesis. This compound matters for its role as a key chiral intermediate in the development of complex pharmaceutical molecules, particularly those targeting the central nervous system. It is primarily needed by research and development chemists, process development teams, and manufacturers in the pharmaceutical and agrochemical industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of potent, selective enzyme inhibitors and receptor modulators.
• Agrochemical Research: Used in the development of novel herbicides and insecticides with specific modes of action.
• Chemical Biology: Serves as a scaffold or precursor for designing molecular probes and tool compounds.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of target APIs.
• Asymmetric Synthesis: Utilized as a starting material or intermediate in catalytic asymmetric transformations.
• Academic & Contract Research: A valuable reagent for methodology development and novel heterocycle construction in academic and CRO settings.

Basic Information

Product Name	1,4-Piperidinedicarboxylic Acid, 4-Methyl-3-Oxo-, 1-(1,1-Dimethylethyl) 4-Ethyl Ester
CAS No.	1168153-63-6
Molecular Formula	C14H23NO5
Molecular Weight	285.34 g/mol
Synonyms	tert-Butyl 4-ethyl 4-methyl-3-oxopiperidine-1,4-dicarboxylate; 1-(tert-Butyl) 4-ethyl 4-methyl-3-oxopiperidine-1,4-dicarboxylate; 4-Methyl-3-oxo-1,4-piperidinedicarboxylic acid 1-tert-butyl 4-ethyl ester; 3-Oxo-4-methylpiperidine-1,4-dicarboxylic acid 1-tert-butyl 4-ethyl ester; 1,4-Piperidinedicarboxylic acid, 4-methyl-3-oxo-, 1-(1,1-dimethylethyl) 4-ethyl ester; 1168153-63-6; 4-Methyl-3-oxo-piperidine-1,4-dicarboxylic acid tert-butyl ethyl ester
EINECS	Contact for details

Quality Control

Our 1,4-Piperidinedicarboxylic Acid, 4-Methyl-3-Oxo-, 1-(1,1-Dimethylethyl) 4-Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are provided for every shipment, and we support customer-specific analytical method validation where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Store away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.